Intermittent Fasting Vs Calorie Restriction for Weight Loss and Insulin Sensitivity

Category Health

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This study by the University of Illinois Chicago found that time-restricted eating (intermittent fasting) led to similar weight loss and improved insulin sensitivity as traditional calorie restriction among adults with obesity, although access to dieticians likely contributed to this effect. Further research is needed to understand individual responses to each dietary intervention.


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A study by the University of Illinois Chicago found that time-restricted eating (intermittent fasting) led to similar weight loss and improved insulin sensitivity as traditional calorie restriction among adults with obesity. Participants in the time-restricted eating group ate fewer calories and lost more weight over a year compared to those who made no changes to their eating habits. Further research is needed to understand individual responses to each dietary intervention.

Intermittent fasting has become increasingly popular in recent years as a weight loss strategy

Obesity is a major health issue. Many traditional weight loss diets involve counting calories, which can be cumbersome and difficult to do well. Time-restricted eating, without calorie counting, has become a popular weight loss strategy because it is simple to do. Whether it’s effective in producing weight loss, especially beyond the short term, is unclear.

Researchers from the University of Illinois Chicago studied 90 adults with obesity from the Greater Chicago area to determine whether intermittent fasting or calorie-restricted eating would be more effective for weight control and cardiometabolic risk reduction.

Insulin sensitivity is improved in those who practised time-restricted eating

Participants were randomly assigned to 1 of 3 groups: 8-hour time-restricted eating (eating from noon to 8:00 p.m. only, without calorie counting); calorie restriction (reduce 25% of their calories daily), or no change in calorie consumption, with eating taking place over 10 hours or more throughout the day. Both the time-restricted eating and calorie-restriction groups met regularly with a dietician. Participants were not blinded.

This study suggests that different diets may work better for different people

The authors found that participants who engaged in time-restricted eating ate 425 fewer calories per day than the control group and lost about 10 more pounds than the control group after one year. The calorie-restricted group ate 405 fewer calories per day and lost about 12 more pounds after one year. Participants showed high adherence to both interventions.

The authors of an accompanying editorial from the Anschutz Health and Wellness Center and Division of General Internal Medicine, University of Colorado School of Medicine say that access to dieticians likely helped participants in the restricted eating group make healthier food choices. They believe the results of this study can help guide clinical decision-making partially by taking individual preferences into consideration, rather than just choosing a diet that may be more effective. They emphasize that the results of this study highlight the substantial individual variability in weight loss using these interventions, and that further research is needed to determine who would most benefit from each of these interventions.

Time-restricted eating is a simple way of eating that does not require calorie-counting

In this study, the University of Illinois Chicago conducted a randomized controlled trial among adults with obesity to investigate the benefits of time-restricted eating and calorie restriction over a period of one year. The study found that participants who engaged in 8-hour time-restricted eating had improved insulin sensitivity and ate 425 fewer calories per day than the control group. Calendar-restricted eating was just as effective as calorie-restriction at inducing weight loss. However, access to dieticians likely had a positive effect on the time-restricted eating group. Further research is needed to determine who would most benefit from each of these interventions.

The study found that participants in both the calorie-restricted and time-restricted eating groups ate 425 and 405 fewer calories per day respectively

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